Program Graduates

The list of program graduates and their doctoral thesis titles is organized by graduation year.


Graduate Name Group Leader Title Of Thesis
Shradha Das Knust Dissecting Crumbs to understand its function in epithelial development of Drosophila embryos
Michaela Mickoleit Huisken Imaging and reconstructing the beating heart and its morphogenesis
Sven Schreiter Tanaka Characterization of photoreceptor outer segments phagocytosis in human embryonic stem cell derived retinal pigment epithelium – and its use as a model for compound screening
Gopi Shah Huisken Pan-embryo Cell Dynamics - Multidimensional imaging uncovers the blueprint of zebrafish development
Anne Morbach Knust The Role of Cdep in the embryonic morphogenesis of Drosophila melanogaster
Andrés Diaz Delgadillo Hyman Temperature drives P granule formation in Caenorhabditis elegans
Tom Stückemann Rink Patterning of the planarian anterior-posterior axis
Antje Petzold Solimena Degradation of insulin secretory granule cargoes and antigen presentation of peptides thereof in Coxsackievirus B5-infected insulin producing cells
Georgios Tsoumpekos Knust big bang, a novel regulator of tissue growth in Drosophila melanogaster
Kirstin Meyer Zerial An in vivo investigation on the mechanosensory function of the mouse liver
Stefania Tavano Huttner Molecular and cellular mechanisms underlying the role of Insm1 in the generation of basal progenitor cells
Sergej Nowoshilow Tanaka Transcriptome analysis of axolotl spinal cord and limb regeneration
Christopher Schmied Tomancak A live imaging paradigm for studying Drosophila development and evolution
Anna Erzberger Salbreux Actomyosin mechanics at the cell level


Graduate Name Group Leader Title Of Thesis
Sarah Mansour Rink Tissue polarity specification in planarians
Stephanie Spannl-Müller Eaton Identification of the protein Ecdysoneless as a regulator of Hedgehog signaling
Rahul Glover Diez Transport by kinesin motors diffusing on a lipid bilayer
Vanessa Carlos Brand Notch signaling in the adult zebrafish brain: a comparative study of neurogenic niches
Mykola Mylenko Kurzchalia Identification and biochemical characterization of food signal in Caenorhabditis elegans
Veronika Fitz Grill Chromatin transcription by RNA polymerase II - nucleosomal geometry matters
Matthias Munder Alberti pH - a key regulator of cellular dormancy?
Orlando Argüello-Miranda Zachariae The regulatory network controlling the transition from prophase I into metaphase I
Sandra Richter Oates A small molecule screen targeting zebrafish somitogenesis
Marta Florio Huttner Transcriptional signatures of neocortical expansion - evolutionary role of the human-specific gene ARHGAP11B
Mattia Brugiolo Neugebauer The dynamic RNA-binding behavior of SR-proteins
Sergii Gaidar Diez Mechanism of one-dimensional protein diffusion along microtubules
Lydia Herzel Neugebauer Co-transcriptional splicing in two yeasts
Anneke Hibbel Howard Characterization of Saccharomyces cerevisiae kinesin Kip2 by total internal reflection fluorescence microscopy
Vladimir Despic Neugebauer Deciphering the post-transcriptional regulatory network during maternal to zygotic transition in zebrafish
Ya-Huei Lin Knust The AP2 complex regulates epithelial polarity via regulating Crumbs endocytosis
Shang-Yun Liu Rink Transcriptomic analysis of molecular wound responses during planarian regeneration
Michael Weber Huisken All-optical 4D in vivo monitoring and manipulation of zebrafish cardiac conduction
Sonja Kroschwald Alberti Promiscuous interactions and redundant assembly pathways promote RNP granule formation in Saccharomyces cerevisiae
Kerstin Schmidt Anastassiadis The role of the H3K4 histone methyltransferase Setd1b during embryogenesis and in adult mice
Sebastian Dunst Eaton Systematic characterization of Rab GTPase cell type expression and subcellular localization in Drosophila melanogaster
Ashish Gupta Stewart Role of H3K4 demethylase Kdm5b in the maintenance of mouse embryonic stem cell pluripotency and neural differentiation
Oliver Wüseke Hyman Pericentriolar material assembly in Caenorhabditits elegans
Jan-Philip Medelnik Tanaka Cellular and molecular effects of lysophosphatidic acid on cultured human neural progenitor cells
Oliver Baker Anastassiadis Adapting Nature's toolbox for genome engineering
Ivan Radin Rödel Functional analysis of the putative mitochondrial copper chaperone AtCox11
Carlos Garzon Coral Howard The forces that center the mitotic spindle in the C. elegans embryo
Özlem Demir Howard Functional characterization of microtubule associated proteins in es cell division and neuronal differentiation
Paulina Strzyz Norden The significance of bringing nuclei to the apical surface for division in the pseudostratified epithelium of the developing zebrafish retina


Title of Thesis
Norman Gerstner Zerial Endocytic modulation of developmental signaling during zebrafish gastrulation
Isabell Weber Norden Committed precursor cells in zebrafish retinal development
Janine Tittel Schwille Actin organization at intracellular membranes: targeting and regulatory interactions of the Spir/formin actin nucleator complex
Aida Rodrigo Albors Tanaka Cellular and molecular mechanisms underlying spinal cord regeneration in Ambystoma mexicanum
Anne Roscher Jessberger SWAP-70 regulates osteoclast function by modulating the actin cytoskeleton
Mansi Gupta Brand Fine-tuning of Fgf8 morphogen gradient by the extracellular matrix
Fong Kuan Wong Huttner Generation of basal radial glia in the embryonic mouse dorsal telencephalon
Melek Kayserili Erkut Tomanczak Investigating evolutionary divergence and quantitative traits in population of early Drosophila melanogaster embryos
Davi Torres Stewart Understanding H3K36 methyltransferases in mouse embryonic stem cells
Sebastian Boland Kurzchalia Regulation of Caenorhabditis elegans development by an interplay between sterols and glycosphingolipids
Liliana Malinovska Alberti Specific adaptations in the proteostasis network of the social amoebae Dictyostelium discoideum lead to an unusual resilience to protein aggregation
Martin Dressler Hyman Dynamics of pericentriolar material during the first cell division of Caenorhabditis elegans embryos
Ana Lisica Grill Single-molecule study of transcription by RNA polymerase I
Ievgeniia Zagoriy Zachariae The Role of Polo-like Kinase in Regulating the Prophase-to-Metaphase Transition of Meiosis I
Martin Sztacho Hoflack F-BAR proteins PSTPIP1 and PSTPIP2 regulate sealing zones in bone resorbing osteoclasts
Uddipta Biswas Jessberger Dissecting the roles of cohesin complexes in murine spermatocytes
Debojyoti Chakraborty Buchholz Systematic dissection of long non coding RNAs involved in the regulation of embryonic stem cell pluripotency
Annelie Oswald Oates Hairy switches and oscillators - reconstructing the Zebrafish segmentation clock
Vaishnavi Ananthanarayanan Tolic-Norrelykke Dynein dynamics during meiotic nuclear oscillations of fission yeast
Martin Machyna Neugebauer The central role of RNA-protein interactions in Cajal body structure and function


Graduate Name Group Leader Title of Thesis
Marija Podolski Howard Characterization of the budding yeast microtubule polymerase Stu2
Peter Hoboth Solimena Novel insights into insulin secretory granule dynamics: The relationship between insulin secretory granule age and the cortical cytoskeleton
Ana Zarzosa Álvarez Tanaka Size control of dorsal root ganglia in developing axolotls
Miguel Turrero Garcia Huttner Analysis of the cell cycle of neural progenitors in the developing ferret neocortex
Oksana Lavrynenko Shevchenko Drosophila ecdysteroidome by LC-MS/MS
Veikko Geyer Howard Characterization of the flagellar beat of the single cell green alga Chlamydomonas reinhardtii
Jonathan Rodenfels Eaton The role of systemically circulating Hedgehog in Drosophila melanogaster
Nikolaos Kyritsis Brand The role of inflammation during zebrafish central nervous system regeneration
Gamze Gunal Jessberger Stage-specific binding profile of cohesin in resting and switch-activated B lymphocytes
Annett Duemmler Tanaka Characterization of pluripotency genes in axolotl spinal cord regeneration
Sophia Millonigg Eckmann The translational activator complex GLD-4/GLS-1 regulates germline stem cell self-renewal and differentiation in the adult C. elegans germ line
Valentina Botti Eckmann Characterization of C. elegans cytoplasmic poly(A) polymerases
Patricia Heyn Neugebauer Nuclear architecture and gene expression during early zebrafish development
Sundar Naganathan Grill Regulation of mesoscale physical properties of the C.elegans actomyosin cortex
Maryam Aliee Jülicher Dynamics and mechanics of compartment boundaries in developing tissues
Daniel Lohmann Thiele Posttranslational modifications of Ancient ubiquitous protein 1 control intracellular lipid droplet clustering
Erdinc Sezgin Schwille Continuously variable lipid packing as the principle of functional membrane heterogeneity
Nagananda Gurudev Knust Identifying genes related to crumbs and elucidating the role of Crumbs in regulating the apical compartment of Drosophila photoreceptor neuron
Dennis Kappei Buchholz Novel telomere binding proteins
Enrico Perini Zerial In vitro reconstitution of the molecular mechanisms of vesicle tethering and membrane fusion
Ana Stevanovic Thiele Structural requirements for targeting of Ancient ubiquitous protein 1 (AUP1) to lipid droplets and discovery of novel regulators of lipid droplet storage
Andrew Clark Paluch Thickness, dynamics and mechanics of the actomyosin cortex
Stephan Saalfeld Tomanczak Towards large scale reconstruction of neuro-anatomy at nanometer resolution
Rene Schneider Diez A novel parabolic prism-type TIR microscope to study gold nanoparticle-loaded kinesin-1 motors with nanometer precision
Martin Bergert Paluch Mechanics of protrusion formation and bleb-based migration in animal cells
Bhavna Rajasekaran Oates Analysis of movement of cellular oscillators in the pre-somitic mesoderm of the zebrafish embryo
Grzegorz Chwastek Schwille Interactions of FCHo2 with lipid membranes
Bo-Kai Liao Oates Quantitative study of deltaD gene dosage in zebrafish somitogenesis
Alexandra Kumichel Knust Epithelial cell polarity in the embryonic hindgut of Drosophila melanogaster
Andreas Hofmann Rödel The mitochondrial phenotype of human mesenchymal stem cells undergoing adipogenic differentiation


Graduate Name Group Leader Title of Thesis
Cihan Erkut Kurzchalia Molecular mechanisms of anhydrobiosis in Caenorhabditis elegans
Iva Kelava Huttner Basal radial glia in mammalian neocortical development - insights into brain evolution
Davide Accardi Tolic-Norrelykke Dynein redistribution during nuclear oscillations in Schizosaccharomyces pombe
Andreas Sagner Eaton Evolution of planar cell polarity during wing development in Drosophila melanogaster
Marcus Jahnel Grill Dual-trap optical tweezers for single molecule studies of transcription
Madina Karimova Buchholz Novel Cre-like site-specific recombinases for genome engineering
Senthil Arumugam Schwille Reconstitution of bacterial cytokinesis - the Z-ring
Shiho Kawamura Mueller Characterization of molecular interactions that switch the functional state of native G protein coupled receptors (GPCRS)
Cornelia Blei Jessberger The role of cohesin SMC1ß and its chromosome association in murine meiosis
Simone Fietz Huttner Neocortex expansion in the human and ferret - a cell biological and molecular analysis of neural progenitors
Marko Storch Howard Characterization of microtubule stability regulating kinesins in vitro and introduction of a high throughput technique for studying kinesins on the single molecule level
Nicole Bieberstein Neugebauer Histone 3 lysine 4 trimethylation and co-transcriptional splicing: a positive feedback loop reinforcing gene expression
Andrej Vasilj Shevchenko Label-free quantitative mass spectrometry for proteomics
Anastasiya Trushko Howard Interaction of XMAP215 with a microtubule plus-end studied with optical tweezers
Ines Wagner Tanaka Identification and proteolytic activation of a serum factor that induces S-phase re-entry in salamander muscle cells
Iana Kalinina Tolic-Norrelykke Kinetochore capture by intranuclear microtubules in Schizosaccharomyces pombe
Maria Begasse Hyman Thermal constrains on the embryonic cell division rate and fitness of nematodes
Jana Sontheimer Pisabarro Functional characterization of proteins involved in cell cycle by structure-based computational methods
Roberto Villasenor Zerial Regulation of signal transduction by endosomal EGFR distribution
Manuel Neetz Tolic-Norrelykke Collective behavior of molecular motors
Stephanie Protze Ravens Transdetermination and lineage reprogramming: promising strategies to generate cardiomyocytes from mature cells?
Francisco Pan-Montojo Funk Effect of rotenone on the enteric nervous system: implication's in Parkinson's disease pathophysiology
Yu Zhu Tanaka Reconstitution of three-dimensional neuroepithelia from mouse and human pluripotent stem cells
Nikolay Samusik Zerial Reconstruction of functional networks from multiparametric high-throughput screens
Xicotencatl Gracida Canales Eckmann Roles of a nuclear hormone receptor during C. elegans germline development
Miguel Coelho Tolic-Norrelykke Ageing by passive aggregation and stochastic distribution of protein aggregates
Zuzana Markova Zachariae Regulation of meiotic prophase by the anaphase-promoting complex


Title of Thesis
Horatiu Fantana Howard Mechanics of spindle centering in Caenorhabditits elegans
Lara Planas Paz Lammert Mechanoinduction of lymph vessel expansion in the developing mouse embryo
Jean Léon Maitre Heisenberg Mechanics of adhesion and de-adhesion in zebrafish germ layer progenitors
Wilhelm Palm Eaton The lipoprotein metabolism of Drosophila melanogaster
Rainer Winnenburg Schröder Mutations and their role in protein interactions and diseases: computational methods for automated retrieval, analysis and application
Alba Diz Muñoz Paluch Role of cell protusions during cell migration in vivo
Joao Firmino Knust A FRAP assay to determine the influence of Crumbs in membrane protein dynamics
Franziska Knopf Weidinger Bone regenerates via dedifferentiation of osteoblasts in the zebrafish fin
Sven Klose Knust Investigation of the signal peptide and establishment of a novel structure-function analysis of crumbs in Drosophila melanogaster
Paulina Aleksandrowicz Schnittler Entry of Ebola virus into host cells
Mate Biro Paluch Mechanics and regulation of cell cortex assembly
Sarah Hochmann Brand The role of Fgf signaling in photoreceptor maintenance and degeneration in the adult zebrafish retina
Volker Kroehne Brand Analysis of brain regeneration in adult zebrafish after traumatic injury
Giovanna Ciotta Stewart Tagging methods as a tool to investigate histone H3 methylation dynamics in mouse embryonic stem cells
Eugeniu Nacu Tanaka Understanding cellular and molecular mechanisms of regeneration in Ambystoma mexicanum (axolotl)
Claire Poulet Ravens Electrophysiological properties of skeletal muscle stem cells: functional evidence of their potential for cardiac differentiation?
Giovanni Marsico Zerial Analysis of the interplay between endocytosis and cell morphology through the development of computational methods
Sider Penkov Kurzchalia Trehalose and trehalose lipids in Caenorhabditis elegans dauer larva
Aurelie Tomczak Pisabarro Discovery of novel chemokines in the human proteome with computational structure-based methods
Ana Isabel Fonseca Hoflack The role of RhoGEFs, FGD6 and Tiam1, on actin and organelle dynamics in resorbing osteoclasts
Radoslaw Ejsmont Tomancak A toolkit for visualization of gene expression in live Drosophila embryos
Stephan Preibisch Tomancak Reconstruction of multi-view microscopic acquisitions
Anja Nitzsche Buchholz Role of Cohesin in the maintenance of embryonic stem cell identity
Fernando Carrillo Oesterreich Neugebauer Co-transcriptional splicing in S.cerevisiae
Anita Bledau Anastassiadis SET histone methyltransferases in mouse embryonic stem cells and mammalian development
Veena Kumari Eaton Discovery of a novel form of Hedgehog that systematically circulates, and its signaling implications in Drosophila
Elena Quesada Hernandez Heisenberg The role of cell division orientation during zebrafish early development


Title of Thesis
Jakub Sedzinski Paluch Mechanics of the polar cell cortex during cytokinesis
Steffen Jänsch Hyman Time-resolved quantification of centrosomes by automated image analysis suggests limiting component to set centrosome size in C. elegans embryos
Maria Rostovskaya Stewart Lineage commitment of conditionally immortalized bone marrow mesenchymal stromal cells from tetracycline-regulated SV40 large t-antigen transgenic mice
Birgit Kagermeier-Schenk Weidinger Genome-wide analysis of Wnt/beta-catenin target genes in zebrafish embryogenesis and characterization of a novel modifier of Wnt signaling pathways
Maciej Paszkowski-Rogacz Buchholz Integration and analysis of phenotypic data from functional screens
Gero Fink Diez Microtubule organisation by active cross-linking proteins
Markus Decker Hyman Setting centrosome size in the early Caenorhabditis elegans embryo
Mario Schöne Thiele Neutral lipid storage in yeast
Daniele Soroldoni Oates Tracking the oscillations of high-fidelity BAC transgenes during zebrafish somitogenesis
Joanna Kalucka Breier Relevance of Prolyl HIF hydroxylase 2 (PHD) during embryo development and wound healing
Mirjam Mayer Grill Mechanics if the C. elegans cell cortex
Helena Khaliullina Eaton Patched-mediated regulation of smoothened trafficking and activity by Lipophorin-derived lipids
Anna Ivanova Solimena New method for distinguishing insulin secretory granules by age
Andreas Ettinger Huttner Release of post-abscission midbodies from stem and cancer cells and potential links to differentiation
Kuei-Fang Chung Bornstein Isolation and characterization of chromaffin progenitor cells from adult adrenal gland
Akhila Chandrashaker Zerial Systems analysis of early endosome motility through identification of molecular motors
Michael Chopin Jessberger Unraveling SWAP-70 functions in B cell ontogeny
Michal Surma Simons Molecular organization of late secretory pathway in Saccharomyces cerevisiae
Shuizi Yu Brand Biophysical characterization of fibroblast growth factor 8 signalling and morphogen gradient formation in vivo
Corina Oswald Rödel Mitochondrial copper homeostasis in mammalian cells
Michael Berndt Diez Optical Near-fields in fluorescence microscopy - techniques to access information in the third dimension on the nanometer scale
Elwy Okaz Zachariae The role of proteolysis in regulating entry into the first division of meiosis
Christian Schroeter Oates Segmentation clock dynamics in zebrafish her gene mutants
Julio Sampaio Simons The role of lipids in cellular architecture and function
Hermann-Josef Kaiser Simons Membrane order and domain formation in cholesterol-containing membranes
Heiko Keller Schwille New in vitro model for studying the influence of HIV-1 gag assembly on lateral membrane organization
Dorian Freudenreich Brand Genetic cell lineage tracing and transcriptome analysis of neuronal progenitor cells during neurogenesis and regeneration of the adult zebrafish telencephalon
Martin Loose Schwille Self-organization of min proteins in vitro
Jan Eglinger Lammert A mechanism of cascular lumen widening revealed by an angiogenesis screen
Judith Schenk Huttner Interkinetic nuclear migration and centrosome positioning in mammalian neural progenitors: the role of non-muscle myosin II
Daniela Roelig Oates The role of the Hes5 gene family in the evolution of the somitogenesis clock
Adriana Klyszejko Mueller Investigating structure and assembly of the energy conversion machinery of the cell by atomic force microscopy
Agata Rybarska Eckmann he novel protein GLS-1 modulates conserved mRNA regulatory machinery and has important roles in C. elegans germline development
Katharina Landsberg Dahmann The role of cell bond tension in directing cell sorting at the anteroposterior compartment boundary in wing imaginal dices of Drosophila melanogaster
Christine Moessinger Thiele Identification, regulation and physiological role of enzymes involved in triacylglycerol and phosphatidylcholine synthesis on lipid droplets
Karolina Jastrezbowska Tomancak Evolution of gene expression regulation during embryonic development of Drosophila species
Livia Goto Silva Zerial Characterization of APPL signalling endosomes in neurons
Nadine Muschalik Knust Epithelial cell polarity and photoreceptor morphogenesis in Drosophila
Garrett Greenan Hyman Setting mitotic apindle length in the early Caenorhabditis elegans embryo


Graduate Name Group Leader Title of Thesis
Thomas Widmann Dahmann The role of Dpp and Wingless signaling gradients in directing cell shape during Drosophila wing imaginal disc development
Estelle Festor Jessberger Role of SMC1beta in meiosis
Jesse Lipp Zachariae Control of reductional chromosome segregation in meiosis
Till Korten Diez How Kinesin-1 deals with roadblocks:biophysical description and nanotechnological application
Vyacheslav Zagoriy Kurzchalia Long chain O-ascarosyl alkendiols (ascarosides) of Caenorhabditis elegans
Magno Junqueira Shevchenko Systematic characterization of mammalian protein complexes by shotgun liquid chromatography tandem mass spectrometry
Annalisa Marsico Schröder Discovery and characterization of new structural and functional motifs in alpha-helical transmembrane proteins with an application to interpret Single Molecule Force Spectroscopy data
Anna Sedello Buchholz Loss-of-functionscreen for proteins cooperating with Runx1 in hematopoiesis and leukemogenesis
Marta Pabis Neugebauer The cap-binding complex promotes co-transcriptional splicing in vivo
Dragomir Krastev Buchholz An RNA interference synthetic interaction screen identifies vulnerability factors for TP53 mutant cells
Manonmani Arunachalam Tomancak Computational discovery of cis-regulatory elements in multiple Drosophila species
Britta Jedamzik Eckmann mRNA targets of GLD-3 in Caenorhabditis elegans
Jens-Christian Roeper Eaton The influence of cell mechanics, cell-cell interactions and proliferation on epithelial packing
Johanna Spandl Thiele Cell biology of lipid droplets: the function of the lipid droplet protein AUP1 and establishment of the novel fluorescent dye LD540 for improved staining and imaging of lipid droplets
Tatsiana Audzevich Jessberger The function of SWP-70 in CD40/IL-4 induced beta cell activation and immunoglobulin E class switch recombination
Waldemar Kanczkowski Bornstein The role of toll-like receptors in the human adrenal gland
Petra Stockinger Heisenberg Regulation of tangentialbranchiomotor neuron migration in zebrafish
Jeremy Pulvers Huttner The roles of the genes Aspm and Brca1 in the development of the mouse neocortex
Christian Klose Simons Membrane organization in yeast
Slava Stamova Rieber Polyclonal tumor-specific activation of cytotoxic effector cells by bispecific antibody constructs
Maria Joao Carvalho Eaton Steraol requirements in Drosophila melanogaster
Julia Massier Thiele siRNA screen for the identification of novel genes regulating lipid droplet metabolism in a human cell line
Falko Riedel Eaton Core members of the Drosophila melanogaster LDL receptor family and their function in wing development
Marzuk Kamal Howard Coupling between membrane-curvature and lipid geometry
Claudio Collinet Zerial Systems survey of endocytosis by functional genomics and quantitative multi-parametric image analysis
Volker Bormuth Howard Optimized optical tweezers to study the mechanics of Kinesin-8: stepping, slipping, protein friction
Charles Bradshaw Zerial Improving the analysis of genome-wide screens trough the detection of weakly conserved domains
Daniel Lingwood Simons The activation of organization in cell membranes
Sven Vogel Tolic-Norrelykke The mechanism of meiotic nuclear oscillations in Schizosaccharomyces pombe
Thomas Hannich Kurzchalia Lipid methylation in the development of Caenorhabditis elegans
Cordula Reuther Diez Patterning planar surfaces with motor proteins: towards spatial control over motile microtubules
Diana Kadner Brand Mechanism of cell adhesion at the midbrain-hindbrain neural plate in the teleost danio rerio
Julia Ganz Brand Subdivisions and molecular characteristics if the neurogenic niches in the adult zebrafish telecephalon
Anne Meyer Reichmann Intracellular signaling pathways in the dopaminergic specification of fetal mesencephalic neural stem cells
Nathalie Wielsch Shevchenko Optimized GeLC-MS/MS for botom-up proteomics
Maria Kolanczyk Brand Signaling mechanisms and developmental function of fibroblast growth factor receptors in zebrafish
Boris Strilic Lammert Molecular mechanism of vascular lumen formation in the dorsal aorta of mice
Stefanie Redemann Hyman The role of the acto-myosin cortex for forcegeneration and spindle positioning in the C.elegans embryo
Fuat Aksoy Pompe Interaction of metal nanoparticles with fluorophores and their effect of fluorescence
Mark Schmid Eckmann GLD-4, a poly(A) polymerase affecting germ development in C. elegans
Fernando Ugarte Verdugo Roesen-Wolff Role of Notch signalling pathway in human mesenchymal stem cell differentiation
Roberto Iacone Anastassiadis Lineage commitment screens in mES cells using a tetracycline inducible cDNS library
Vladimir Mazurov Tanaka Lineage commitment screens in mES cells using a tetracycline inducible cDNS library


Title of Thesis
Bert Nitzsche Diez Optical 3D-nanometry to study the function of biomolecular motors in nanotransport
Natalya Baltrukovich Mueller Mechanical unfolding of membrane proteins captured with single-molecule AFM techniques
Magalie Lebreton Kurzchalia New outlooks on the transport of cholesterol in Caenorhabditis elegans
Leah Herrgen Oates The regulation of segmentation clock period in zebrafish
Jifeng Fei Huttner Studies on the progeny of neuronal progenitors in the developing mouse brain using novel transgenic models of the tis21 locus
Ana Fonseca Corbeil New insights into cell migration and asymmetric cell division of human hematopoietic progenitors
Konstantin Doubrovinski Kruse Physical approaches to cytoskeletal self-organization
Adam Kupinski Eckmann The Ste20 kinease GCK-3 is essential for C. elegans development and regulates centrosome maturation during meiosis
Mathias Gerl Simons Membrane domains and traffic in epithelial cells
Mikolaj Slabicki Buchholz A systematic investigation of DNA double strand break repair by a genome-wide RNAi screen in human cells
Sabine Buschhorn Simons Functional implication of lipid organization in MDCK cells
Axel Erler Stewart Family ties: characterization of DNA annealing protein reveal a new model or the initiation of homologous recombination
Philipp Weissert Tanaka Bmp proteins in urodele myotube cell cycle re- entry and in regeneration
Christin Suess Solimena mRNA binding proteins as early response factors of stimulated insulinoma INS-1 cells
Julia Winter Zerial Genome-wide analysis of membrane trafficking in polarised epithelial cells in the C.elegans intestine
Magdalena Strzelecka Neugebauer The essential role of cajal bodies in embryonic development
Luke Buchanan Stewart Mechanisms of chromatin state definition in Schizosaccharomyces pombe
Maria Aranzazu Sanchez Fernandez Pompe Role of osteoclasts in bone formation and bone microenvironment
Zuzana Kirsnerova Baretton The role of Hypoxia inducible factors in physiological and pathological angiogenesis
Marta Luz Brand Cellular mechanisms involved in Wnt8 distribution and function in zebrafish neurectoderm patterning
Fernando Fierro Becker Ehninger Definition of molecular pathways with importance for the interaction of leukemic blasts with mesenchymal stem cells
Vladimir Varga Howard Characterization of Saccharomyces cerevisiae kinesin-8 by single-molecule fluorescene microscopy
Tobias Heckel Hoflack Revealing Src tyrosine kinase-dependent signaling pathways in osteoclasts: Implications on actin organization and cell polarity


Title of Thesis
Sina Koch Ehninger Aberrant subcellular localization as a potential mechanism contributing to the abnormal signaling of the mutant Flt3-ITd receptor tyrosine kinase in acute myeloid leukemia
Susanne Mende Reichmann Alterations in nuclear gene expression profiles in response to mitochondrial dysfunction
Marcello Maresca Stewart Fundamental and applied studies on phage mediated recombination
Jakob Suckale Solimena Polypyrimidine tract-binding protein in knockdown mouse models
Lara Carvalho Heisenberg The role of yolk syncytial layer in blastoderm movements during gastrulation in zebrafish
Nicola Bauer Corbeil New insights into the plasma membrane dynamics of rare stem cells by studying the prominin molecule
Yvonne Gloor Walch-Solimena The Arf GTPase exchange factor sec7p interaction network: unraveling the crosstalk between key regulators of golgi transport
Joao Matos Zachariae Regulation of chromosome segregation in meiosis
Cagri Sakalar Stewart The role of H2A.z in fission yeast chromatin
Amani Said Dahmann Mechanisms underlying cell sorting at the A-P compartment boundary in the Drosophila wing
Ruiyu Zhu Rieber Molecular analysis of a RNA surveillance escape mechanism leading to systemic autoimmunity
Martin Kragl Tanaka Studying the patterning mechanisms and cell fates during limb regeneration in Ambystoma mexicanum
Thomas Ohrt Schwille Elucidating the intracellular mechanisms of RNA interference by single molecule fluorescence microscopy and spectroscopy
Vinciane Grimard Thiele MAPK9: A new regulator of triglyceride metabolism revealed by siRNA screening
Eva-Maria Schoetz Heisenberg Dynamics and mechanics of zebrafish embryonic tissues
Jennifer Fish Huttner The evolution of neuronal progenitor cell division in mammals: the role of the abnormal spindle-like microcephaly associated (Aspm) protein and epithelial cell polarity
David Cisneros Armas Mueller Molecular assemblies observed by atomic force miscroscopy
Serap Günes   Modification of vesicular stomatitis virus G protein for targeted gene delivery into PSCA-positive tumor cells
Anne-Lore Schlaitz Hyman Setting mitotic spindle length in the early Caenorhabditis elegans embryo
Robin Klemm Simons Lipid rafts in protein sorting and yeast cell polarity
Raluca Constantinescu Reichmann Oxidative stress involvement in new cell culture models of Parkinson´s disease
Ana Cunha Rieber Evaluation of D-TMPP for use in diagnosis and specific cellular immunotherapy of prostate cancer
Nicola Watt Reichmann Mitochondrial dysfunction and lipid metabolism in cell culture models of respiratory chain and neurodegenerative diseases
Tim Noetzel Hyman Control of microtubule dynamics by XMAP215 and XTACC3
Tanuj Sapra Mueller Single-molecule measurements of complex molecular interactions in membrane proteins using atomic force microscopy
Laura Buffa Solimena Cell biology of the ICA69 protein family in neurosecretory cells
Christer Ejsing Simons Molecular characterization of the lipidome by mass spectrometry
Anna Grzyb Huttner Characterization of Y-box protein 3 (MSY3) in the developing murine central nervous system
Susanne Bechstedt Howard Mechanotransduction in Drosophila melanogaster
Henrik Bringmann Howard Experiments concerning the mechanism of cytokinesis in Caenorhabditis elegans embryos


Title of Thesis
Alessio Attardo Huttner Novel in vivo imaging approaches to study embryonic and adult neurogenesis in the mouse
Mihail Sarov Stewart A recombineering pipeline for functional genomics applied to Caenorhabditis elegans
Heather Mortiboys Reichmann Influence of mitochondrial energy metabilism on cellular function: implication for neurometabolic and neurodegenerative diseases
Coralie Apfeldorfer Hoflack Lyosome biogenesis during osteoclastogenesis
Alexej Kedrov Mueller Observing molecular interactions that determine stability, folding, and functional states of single Na+/H+ antiporters
Gaspare Benenati Kurzchalia Osmotic balance and establishment of polarity in the C.elegans embryo require cytochrome P450 CYP31A
Alvaro Crevenna Howard Kinesin-1 mechanical flexibility and motor cooperation
Sabine Witzel Heisenberg Local WNT11 signalling and its role in coordinating cell behaviour in zebrafish embryos
Christina Eugster Eaton The glypican Dally binds to Lipophorin particles and increases Hedgehog signaling efficiency
Ralf Kittler Buchholz Functional genomic analysis of cell cycle progression in human tissue culture cells
Irena Konstantinova Lammert EphA-ephrin-A bidirectional signaling amplifies insulin secretion from beta-cells
Maike Gravert Walch-Solimena Novel regulators of trafficking in the yeast Golgi-endosomal system
Indrani Sarkar Buchholz Directed evolution of an HIV-1 LTR specific recombinase for anti-retroviral therapy - a proof of concept study
Lucie Kalvodova Simons Reconstituting APP and BACE in proteoliposomes to characterize lipid requirements for beta-secretase activity
Thorsten Baust Hoflack Proteomic analysis of the sorting machineries involved in vesicular traffic between the biosynthetic
Ganka Nikolova Lammert The vascular basement membrane: a niche for insulin gene expression and beta cell proliferation
Anne-Kathrin Classen Eaton Hexagonal packing of Drosophila wing epithelial cells by the planar cell polarity pathway
Imke Listerman Neugebauer On co-transcriptional splicing and U6 snRNA biogenesis
Serena Bielli Dahmann Characterization of the EGFL7/8 ortholog during Drosophila oogenesis
Fabio Demontis Dahmann Modeling human Usher syndrome during Drosophila melanogaster development
Werner Straube Tanaka Purification of a serum factor that triggers cell cycle re-entry in differential newt myotubes
Cerasela Dinu Howard Leveraging the motor protein Kinesin to manipulate DNA molecules in synthetic environment
Lidia Sobkow Tanaka Development of transgenic Ambystoma mexicanum (axolotl) to study fate during development and regeneration
Sandra Schubert Solimena The role of Beta2-syntrophin phosphorylation in secretory granule exocytosis
Vinzenz Link Heisenberg Identification of proteins controlling gastrulation movements by a proteomic approach in zebrafish
Tobias Oelschlaegel Zachariae Meiosis-specific regulations of the anaphase-promoting complex
Ihor Zahanich Ravens Differentiation potential of human mesenchymal stem cells: expression of molecular markers, ion channels and gap junction channels
Oleh Khalimonchuk Rödel Yeast mitochondrail copper metabolism: topology ND ROLE OF COX11P
Naomi Foster Gonzalez The involvement of ARF6 in rapid membrane recycling during Drosophila spermatocyte cytokinesis


Title of Thesis
Andriy Kovalchuk Barth Molecular analysis of the LTR retrotransposon Ylt1 from the genome of dimorphic fungus Yarrowia lipolytica
Sandra Lubitz Stewart Analysis of an epigenetic regulator in mouse embryonic stem cell - self-renewal and differentiation
Stephanie Schonegg Hyman Rho GTPase family members in establishment of polarity in C. elegans embryos
Sebastian Höpfner Zerial Modulation of cargo transport and sorting through endosome motility and positioning
Bartosz Balana Ravens Influence of culture conditions on differentiation and bioelectrical properties of human mesenchymal stem cells
Nurhan Ozlu Hyman The mitotic spindle assembly in C. elegans embryos
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Monika Suchanek Thiele Regulation of lipid homeostasis - mechanisms of sterol sensing
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